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Abstract: Particle swarm optimization (PSO ) is an effective & reliable evolutionary based approach . Yuhui Shi and Russell Eberhart "A modified particle swarm optimizer" 0- 7803-4869-9198 0.0001998 IEEE. Key words: docking, homology modeling, leprosy, M.leprae, molecular, molecular dynamics, ramachandran plot. Therefore identification of the novel drug target and potent drug can be helpful in better prevention of the disease. Alter et.al, (2008) Leprosy as a genetic model for susceptibility to common infectious disease, Hum Genet 2. (1999)Health Policy and Planning; 14(2): 89-102, Oxford University Press. This causes a lot of heat generation and energy loss within the actuators. The study investigates and analyzes the possibilities of reducing the hydraulic resistance and increasing efficiency of the hydraulic actuator.
Results show that the small outlet ports are the sources of energy loss in hydraulic cylinders. The proposed four ports cylinder was simulated and parameters such as ports sizes, loads and pressures are varied during the simulation.