Her husband, who she wed in a Scientologist ceremony in 2015, was giving her a helping hand as they unloaded their possessions from out of the boot of a car.
The pair were also seen popping into a corner shop to pick up some breakfast essentials in the midst of their busy weekend.
The 24-year-old and her IT consultant partner were spotted moving into their modest new abode on Sunday, without even enlisting the help of removal men.
Isabella was clad in a low-key ensemble, sporting a baggy grey jumper and black jeans.
Your destinies somehow all come together.'Cruise, 55, also has an 11-year-old daughter, Suri, by third wife Katie Holmes.
Born in Croydon, Greater London, she was discovered in 1988 at age 14 by Sarah Doukas, founder of Storm Model Management, at JFK Airport in New York City.
In 2015, Woman's Day reported that Isabella has settled into conjugal life in a quiet corner of the south London city - the birth place of model Kate Moss - after shunning the glitz and glamour of her formative years.
Her husband's home turf: Isabella's new environs has been home for more than 20 years to her husband's family; his father is a test pilot at Gatwick Airport, while his mother works as an antiques restorer Isabella was notably estranged from her Australian mother for years, but is reportedly now back in contact.
The snake motif style Isabella Cruise is wearing here is by RVCA, a brand whose fan club includes Lindsay Lohan and Vanessa Hudgens.
Instead of the sprawling, gated property in Los Angeles favoured by her famous parents, Isabella opted for a more modest, one story family home with breeze block facade.